Category: Nursing

  • [Solved] soap note

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    **Problem-Focused SOAP Note Format** **Demographic Data** – Age and gender (must be HIPAA compliant) **Subjective** – Chief Complaint (CC): A short statement about why they are there – History of Present Illness (HPI): Write your HPI in paragraph form. Start with the age, gender, and why they are th…

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    Assignment Prompt & Instructions

    **Problem-Focused SOAP Note Format**

    **Demographic Data**

    – Age and gender (must be HIPAA compliant)

    **Subjective**

    – Chief Complaint (CC): A short statement about why they are there
    – History of Present Illness (HPI):  Write your HPI in paragraph form. Start with the age, gender, and why they are there (example: 23-year-old female here for…). Elaborate using the acronym OLDCART: Onset, Location, Duration, Characteristics, Aggravating/Alleviating Factors, Relieving Factors, Treatment
    – Past Med. Hx (PMH): Medical or surgical problems, hospitalizations, medications, allergies, immunizations, and preventative health maintenance
    – Family Hx: any history of CA, DM, HTN, MI, CVA?
    – Social Hx: Including nutrition, exercise, substance use, sexual hx, occupation, school, etc.
    – Review of Systems (ROS) as appropriate: Include health maintenance (e.g., eye, dental, pap, vaccines, colonoscopy)

    **Objective**

    – Vital Signs
    – Physical findings listed by body systems, not paragraph form- Highlight abnormal findings

    **Assessment (the diagnosis)**

    – At least Two (2) differential diagnoses (if applicable) with rationale and pertinent positives and negatives for each
    – Final diagnosis with rationale, pertinent positives and negatives, and pathophysiological explanation

    **Plan**

    – Dx Plan (lab, x-ray)
    – Tx Plan (meds): including medication(s) prescribed (if any), dosage, frequency, duration, and refill(s) (if any)
    – Pt. Education, including specific medication teaching points
    – Referral/Follow-up
    – Health maintenance: including when screenings eye, dental, pap, vaccines, immunizations, etc. are next due

    **Reference**

    – Compare care given to the patient with the National Standards of Care/National Guidelines. Cite accordingly.

    – 2 years ago

  • [Solved] week 6

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    In-depth study guidance and analytical solution covering week 6.

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    Assignment Prompt & Instructions

    Full assignment prompt and step-by-step guidance are included in the downloadable solution file.

  • [Solved] Discussion – Cultural Assessment

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    Criteria 1. Summarize the cultural assessment of your selected country in 1 – 2 paragraphs. 2. Described similar patterns or themes noticed with the cultural self-assessment (identify your cultural background). 3. Described the differences found with your cultural self-assessment. 4. Described the o…

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    Assignment Prompt & Instructions

    Criteria

    1. Summarize the cultural assessment of your selected country in 1 – 2 paragraphs.
    2. Described similar patterns or themes noticed with the cultural self-assessment (identify your cultural background).
    3. Described the differences found with your cultural self-assessment.
    4. Described the one new characteristic that was learned about the chosen culture.
    5. Explained how the information learned about the chosen culture could be incorporated into the nursing plan of care. Include at least one (1) scholarly resource dated within the past five seven (7) years to support your response.

    – [\
    \
    76081008172__72E6B997-3794-45C5-8C1A-C6A1477AB986.jpeg](https://www.sweetstudy.com/files/76081008172-72e6b997-3794-45c5-8c1a-c6a1477ab986-jpeg "76081008172__72E6B997-3794-45C5-8C1A-C6A1477AB986.jpeg")
    – [\
    \
    Screenshot2025-02-10102433.png](https://www.sweetstudy.com/files/screenshot2025-02-10102433-png "Screenshot2025-02-10102433.png")

    – 2 years ago

  • [Solved] Vital Organs & Unconscious State

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    After studying the course materials located on [Module 5: Lecture Materials & Resources](https://stu.instructure.com/courses/44227/pages/module-5-lecture-materials-and-resources "Module 5: Lecture Materials & Resources") page, answer the following: 1. Name some very important organs that are not vit…

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    Assignment Prompt & Instructions

    After studying the course materials located on [Module 5: Lecture Materials & Resources](https://stu.instructure.com/courses/44227/pages/module-5-lecture-materials-and-resources "Module 5: Lecture Materials & Resources") page, answer the following:

    1. Name some very important organs that are not vital organs.
    2. List the functional description of all the normal vital organs, including today’s exceptions.
    3. Is it possible to live without a vital organ? Why? Example?
    4. Distinction between assisting or substituting vital organs. Bioethical analysis.
    5. Do the following practices assist or substitute the vital organ? Why?
    – Dialysis
    – Respirator
    – Ventilator
    – Tracheotomy
    – CPR
    6. Read and summarize ERD PART FIVE Introduction.
    7. Unconscious state: Definition.
    8. Clinical definitions of different states of unconsciousness: Compare and contrast
    9. Benefit vs Burden: bioethical analysis.

    – 2 years ago

  • [Solved] Vital Organs & Unconscious State

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    Executive Solution Overview

    After studying the course materials located on [Module 5: Lecture Materials & Resources](https://stu.instructure.com/courses/44227/pages/module-5-lecture-materials-and-resources "Module 5: Lecture Materials & Resources") page, answer the following: 1. Name some very important organs that are not vit…

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    Assignment Prompt & Instructions

    After studying the course materials located on [Module 5: Lecture Materials & Resources](https://stu.instructure.com/courses/44227/pages/module-5-lecture-materials-and-resources "Module 5: Lecture Materials & Resources") page, answer the following:

    1. Name some very important organs that are not vital organs.
    2. List the functional description of all the normal vital organs, including today’s exceptions.
    3. Is it possible to live without a vital organ? Why? Example?
    4. Distinction between assisting or substituting vital organs. Bioethical analysis.
    5. Do the following practices assist or substitute the vital organ? Why?
    – Dialysis
    – Respirator
    – Ventilator
    – Tracheotomy
    – CPR
    6. Read and summarize ERD PART FIVE Introduction.
    7. Unconscious state: Definition.
    8. Clinical definitions of different states of unconsciousness: Compare and contrast
    9. Benefit vs Burden: bioethical analysis.

    – 2 years ago

  • [Solved] discussion

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    In-depth study guidance and analytical solution covering discussion.

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    Assignment Prompt & Instructions

    Full assignment prompt and step-by-step guidance are included in the downloadable solution file.

  • [Solved] B-HEALTH DISPARITIES

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    **Assignment Overview** Select one low- or middle-income country, and investigate the health disparities experienced by people living in that region. Identify one disparity as the topic for this assignment, and investigate that disparity to learn more about the contributing factors and the impact of…

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    Assignment Prompt & Instructions

    **Assignment Overview**

    Select one low- or middle-income country, and investigate the health disparities experienced by people living in that region. Identify one disparity as the topic for this assignment, and investigate that disparity to learn more about the contributing factors and the impact of the disparity on the health of people living in that region. Consider how this issue is similar to and different in a high income country of your choosing, and investigate interventions to reduce the disparity.

    In a **10 slides PowerPoint** **presentation**, address the following elements. Include a minimum of **4** scholarly sources, current within 5 years, to support your work. **See rubric AND INSTRUCTIONS ATTACHED for specific, required content criteria within each section of the presentation**:

    1. Provide an introduction to the presentation.
    2. Provide an overview of the selected health disparity, the factors that contribute to the disparity, and the overall impact of the disparity on the health and well-being of people in that region.
    3. Describe how this issue is similar and different in a selected high income country, and explain the reasons for those similarities and differences.
    4. Discuss at least two interventions to reduce the disparity, and explain how international health collaboration can promote health equity.
    5. Provide a conclusion to the presentation.

    **Assignment Instructions**

    1. Abide by the Chamberlain College of Nursing Academic Integrity Policy no more than 10% PLAGIO.
    2. Use Microsoft PowerPoint to create the presentation.
    3. Each slide (excluding title and reference slides) must include detailed speaker notes.
    1. The purpose of the speaker notes is to expand upon the idea and document facts and information about the bulleted information points on the slide.
    2. Formal, scholarly writing style with complete sentence and paragraph structure should be used to create the speaker notes.
    3. Scholarly literature support should be integrated within the speaker notes.
    4. Speaker notes assure that all assignment expectations and key points are covered.
    4. Within the speaker notes, the rules of grammar, spelling, word usage, punctuation, sentence and paragraph structure are followed and consistent with formal, scholarly writing as noted in the APA Manual (current edition).
    5. First person should not be used for this scholarly assignment.
    6. Citation and referencing of sources must be congruent with guidelines noted in the APA Manual (current edition).
    7. Slides are professional in appearance with visually balanced text, font appropriate for audience reading, succinct bulleted points, and visually appealing contrast between background and font utilized. Correct spelling and appropriate use of graphics/images is evident.
    8. **Sources older than five years may not be used without the permission of the class professor.**

    **I NEED THE SLIDES WITH CONDENSED INFORMATION, NOT ALMOST EMPTY, AND EACH ONE WITH SPEAKER NOTE AS REQUIRED PLEASE**

    – [\
    \
    INSTRUCTIONSANDRUBRIC.pdf](https://www.sweetstudy.com/files/instructionsandrubric-pdf-10187631 "INSTRUCTIONSANDRUBRIC.pdf")

    – 2 years ago

  • [Solved] a description of the significance of the practice gap, your PICO question,

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    Submit a description of the significance of the practice gap, your PICO question, and the PDFs of the 4 primary research articles you identified from your literature search. PICO question “ **Among elderly patients aged 65 and over with chronic renal failure/ESRD, does implementing detailed discharg…

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    Assignment Prompt & Instructions

    Submit a description of the significance of the practice gap, your PICO  question, and the PDFs of the 4 primary research articles you identified from your literature search.

    PICO question

    “ **Among elderly patients aged 65 and over with chronic renal failure/ESRD, does implementing detailed discharge instruction and outpatient follow- up, compared to traditional discharge without detailed instruction and plans for outpatient follow-up reduce 30-days hospital readmission rate”?**

    – 2 years ago

  • [Solved] 4k15 patho

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    – 2 years ago **files (1)** – ## Assessment2patho.docx **## Assessment2patho.docx** **Assessment 2** **Enhancing Holistic Nursing Care With the 3Ps** Create a 3–5 page double-spaced paper that examines how holistic nursing care and pathophysiology, pharmacology, and physical assessment intersect to …

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    Assignment Prompt & Instructions

    – 2 years ago

    **files (1)**

    – ## Assessment2patho.docx

    **## Assessment2patho.docx**

    **Assessment 2**

    **Enhancing Holistic Nursing Care With the 3Ps**

    Create a 3–5 page double-spaced paper that examines how holistic nursing care and pathophysiology, pharmacology, and physical assessment intersect to help nurses provide safe and quality care.

    Expand All

    **Introduction**

    Holistic nursing care is crucial for driving positive health outcomes because it considers the whole person, including their physical, emotional, social, and spiritual needs. This comprehensive approach allows for more personalized care, leading to better patient satisfaction and improved health outcomes. For Bachelor of Science in Nursing (BSN) nurses, understanding holistic nursing care is vital as it equips nurses with the skills to provide comprehensive care, enhancing their ability to promote health and wellness effectively. Furthermore, a solid understanding of pathophysiology, pharmacology, and physical assessment is essential in providing evidence-based holistic nursing care. Together, these elements enable nurses to develop a comprehensive care plan that addresses all aspects of a patient's health, thereby promoting holistic care and improving patient outcomes.

    **Instructions**

    For this assessment you will be creating a paper that explores holistic nursing care and how pathophysiology, pharmacology, and physical assessment play a role in delivering holistic care. Your paper should be 3–5 double spaced pages, not counting the title or reference page. You should also be prepared to support your paper with evidence from the literature and professional best practices.

    Your assessment submission will be assessed on the following criteria:

    · Define holistic nursing care.

    ·
    **Definition of Holistic Nursing Care and its Benefits for Patients and Nurses:** The section should provide a clear definition of holistic nursing care and explain its benefits for both patients and nurses. The definition should be accurate and comprehensive, and the benefits should be supported by evidence-based research.

    · Explain how pathophysiology can help nurses understand the underlying causes and mechanisms of diseases and disorders, and how they affect the whole person.

    ·
    **Explanation of Pathophysiology and Its Role in Nursing Practice:** This section should explain how pathophysiology can help nurses understand the underlying causes and mechanisms of diseases and disorders, and how they affect the whole person. The explanation should be detailed and supported by relevant examples.

    · Discuss how pharmacology can help nurses select, administer, and monitor the effects of medications, and how they interact with the patient’s physical, psychological, and social needs.

    ·
    **Discussion of Pharmacology and Its Role in Nursing Practice:** This section should discuss how pharmacology can help nurses select, administer, and monitor the effects of medications, and how they interact with the patient’s physical, psychological, and social needs. The discussion should be comprehensive and supported by relevant examples.

    · Describe how nurses can use physical assessment to collect, analyze, and interpret data about the patient’s health status, and how they can use this information to plan, implement, and evaluate care.

    ·
    **Description of Physical Assessment and Its Role in Nursing Practice:** This section should describe how physical assessment can help nurses collect, analyze, and interpret data about the patient’s health status, and how they can use this information to plan, implement, and evaluate care. The description should be detailed and supported by relevant examples.

    · Identify two examples of how these three domains of knowledge (pathophysiology, pharmacology, and physical assessment) can be integrated and applied in different clinical scenarios and settings.

    ·
    **Examples of Integration and Application of Knowledge in Clinical Scenarios:** This section should provide examples of how these three domains of knowledge (pathophysiology, pharmacology, and physical assessment) can be integrated and applied in different clinical scenarios and settings. The examples should be relevant and supported by evidence-based research.

    · Convey purpose, in an appropriate tone and style, incorporating supporting evidence and adhering to organizational, professional, and scholarly writing standards.

    **Additional Requirements**

    ·
    **Length of submission:** 3–5 pages of content plus title and reference pages.

    ·
    **Number of references:** Cite a minimum of 4 sources of scholarly or professional evidence that support your findings and considerations. Resources should be no more than 5 years old. Use the
    [Capella University Library](https://lat.strategiced.com/redirect?linkid=1651) and
    [BSN Program Library Research Guide](https://capellauniversity.libguides.com/BSN) as needed.

    ·
    **APA formatting:** References and citations are formatted according to current APA style. See the
    [APA Module](https://lat.strategiced.com/redirect?linkid=2586).

    **Competencies Measured**

    By successfully completing this assessment, you will demonstrate your proficiency in the following course competencies and scoring guide criteria:

    · Competency 1: Explain how pathophysiology, pharmacology, and physical assessment comprise a holistic approach to nursing care.

    · Define holistic nursing care.

    · Explain how pathophysiology can help nurses understand the underlying causes and mechanisms of diseases and disorders, and how they affect the whole person.

    · Discuss how pharmacology can help nurses select, administer, and monitor the effects of medications, and how they interact with the patient's physical, psychological, and social needs.

    · Identify two examples of how these three domains of knowledge (pathophysiology, pharmacology, and physical assessment) can be integrated and applied in different clinical scenarios and settings.

    · Competency 2: Create evidence based interventions to address the health needs, risks, and resources of individuals from diverse backgrounds and cultures.

    · Describe how nurses can use physical assessment to collect, analyze, and interpret data about the patient’s health status, and how they can use this information to plan, implement, and evaluate care.

    · Competency 5: Apply scholarly writing standards to communicate evidence based strategies that support safe and effective patient care.

    · Convey purpose, in an appropriate tone and style, incorporating supporting evidence and adhering to organizational, professional, and scholarly writing standards.

    **## Assessment2patho.docx**

    **Assessment 2**

    **Enhancing Holistic Nursing Care With the 3Ps**

    Create a 3–5 page double-spaced paper that examines how holistic nursing care and pathophysiology, pharmacology, and physical assessment intersect to help nurses provide safe and quality care.

    Expand All

    **Introduction**

    Holistic nursing care is crucial for driving positive health outcomes because it considers the whole person, including their physical, emotional, social, and spiritual needs. This comprehensive approach allows for more personalized care, leading to better patient satisfaction and improved health outcomes. For Bachelor of Science in Nursing (BSN) nurses, understanding holistic nursing care is vital as it equips nurses with the skills to provide comprehensive care, enhancing their ability to promote health and wellness effectively. Furthermore, a solid understanding of pathophysiology, pharmacology, and physical assessment is essential in providing evidence-based holistic nursing care. Together, these elements enable nurses to develop a comprehensive care plan that addresses all aspects of a patient's health, thereby promoting holistic care and improving patient outcomes.

    **Instructions**

    For this assessment you will be creating a paper that explores holistic nursing care and how pathophysiology, pharmacology, and physical assessment play a role in delivering holistic care. Your paper should be 3–5 double spaced pages, not counting the title or reference page. You should also be prepared to support your paper with evidence from the literature and professional best practices.

    Your assessment submission will be assessed on the following criteria:

    · Define holistic nursing care.

    ·
    **Definition of Holistic Nursing Care and its Benefits for Patients and Nurses:** The section should provide a clear definition of holistic nursing care and explain its benefits for both patients and nurses. The definition should be accurate and comprehensive, and the benefits should be supported by evidence-based research.

    · Explain how pathophysiology can help nurses understand the underlying causes and mechanisms of diseases and disorders, and how they affect the whole person.

    ·
    **Explanation of Pathophysiology and Its Role in Nursing Practice:** This section should explain how pathophysiology can help nurses understand the underlying causes and mechanisms of diseases and disorders, and how they affect the whole person. The explanation should be detailed and supported by relevant examples.

    · Discuss how pharmacology can help nurses select, administer, and monitor the effects of medications, and how they interact with the patient’s physical, psychological, and social needs.

    ·
    **Discussion of Pharmacology and Its Role in Nursing Practice:** This section should discuss how pharmacology can help nurses select, administer, and monitor the effects of medications, and how they interact with the patient’s physical, psychological, and social needs. The discussion should be comprehensive and supported by relevant examples.

    · Describe how nurses can use physical assessment to collect, analyze, and interpret data about the patient’s health status, and how they can use this information to plan, implement, and evaluate care.

    ·
    **Description of Physical Assessment and Its Role in Nursing Practice:** This section should describe how physical assessment can help nurses collect, analyze, and interpret data about the patient’s health status, and how they can use this information to plan, implement, and evaluate care. The description should be detailed and supported by relevant examples.

    · Identify two examples of how these three domains of knowledge (pathophysiology, pharmacology, and physical assessment) can be integrated and applied in different clinical scenarios and settings.

    ·
    **Examples of Integration and Application of Knowledge in Clinical Scenarios:** This section should provide examples of how these three domains of knowledge (pathophysiology, pharmacology, and physical assessment) can be integrated and applied in different clinical scenarios and settings. The examples should be relevant and supported by evidence-based research.

    · Convey purpose, in an appropriate tone and style, incorporating supporting evidence and adhering to organizational, professional, and scholarly writing standards.

    **Additional Requirements**

    ·
    **Length of submission:** 3–5 pages of content plus title and reference pages.

    ·
    **Number of references:** Cite a minimum of 4 sources of scholarly or professional evidence that support your findings and considerations. Resources should be no more than 5 years old. Use the
    [Capella University Library](https://lat.strategiced.com/redirect?linkid=1651) and
    [BSN Program Library Research Guide](https://capellauniversity.libguides.com/BSN) as needed.

    ·
    **APA formatting:** References and citations are formatted according to current APA style. See the
    [APA Module](https://lat.strategiced.com/redirect?linkid=2586).

    **Competencies Measured**

    By successfully completing this assessment, you will demonstrate your proficiency in the following course competencies and scoring guide criteria:

    · Competency 1: Explain how pathophysiology, pharmacology, and physical assessment comprise a holistic approach to nursing care.

    · Define holistic nursing care.

    · Explain how pathophysiology can help nurses understand the underlying causes and mechanisms of diseases and disorders, and how they affect the whole person.

    · Discuss how pharmacology can help nurses select, administer, and monitor the effects of medications, and how they interact with the patient's physical, psychological, and social needs.

    · Identify two examples of how these three domains of knowledge (pathophysiology, pharmacology, and physical assessment) can be integrated and applied in different clinical scenarios and settings.

    · Competency 2: Create evidence based interventions to address the health needs, risks, and resources of individuals from diverse backgrounds and cultures.

    · Describe how nurses can use physical assessment to collect, analyze, and interpret data about the patient’s health status, and how they can use this information to plan, implement, and evaluate care.

    · Competency 5: Apply scholarly writing standards to communicate evidence based strategies that support safe and effective patient care.

    · Convey purpose, in an appropriate tone and style, incorporating supporting evidence and adhering to organizational, professional, and scholarly writing standards.

  • [Solved] Evidence-Based Approach

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    – 2 years ago **files (2)** – ## C5A3Instructions.docx – ## C5A3Example.pdf **## C5A3Instructions.docx** **Instructions:** After reviewing the materials you created to research a specific diagnosis in the first two assessments, apply the PICO(T) process to develop a research question and research it…

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    – 2 years ago

    **files (2)**

    – ## C5A3Instructions.docx

    – ## C5A3Example.pdf

    **## C5A3Instructions.docx**

    **Instructions:**

    After reviewing the materials you created to research a specific diagnosis in the first two assessments, apply the PICO(T) process to develop a research question and research it.

    Your initial goal is to define the population, intervention, comparison, and outcome. In some cases, a time frame is relevant and you should include that as well, when writing a question you can research related to your issue of interest. After you define your question, research it, and organize your initial findings, select the two sources of evidence that seem the most relevant to your question and analyze them in more depth. Specifically, interpret each source's specific findings and best practices related to your chosen diagnosis, and explain how the evidence would help you plan and make decisions related to your question.

    If you need some structure to organize your initial thoughts and research, the PICOT Question and Research Template document (accessible from the "Create PICO(T) Questions" (BELOW) page in the Capella library's Evidence Based Practice guide) might be helpful.

    In your submission, make sure you address the following grading criteria:

    · Define a practice issue to be explored via a PICO(T) approach. Create a PICO(T)-formatted research question

    · Identify sources of evidence that could be potentially effective in answering a PICO(T) question (databases, journals, websites, etc.).

    · Explain the findings from articles or other sources of evidence as it relates to the identified health care issue.

    · Explain the relevance of the findings from chosen sources of evidence to making decision related to a PICO(T) question.

    · Communicate using writing that is clear, logical, and professional with correct grammar and spelling using the current APA style.

    **Create PICO(T) Questions:**

    **PICOT QUESTION PROCESS**

    Creating a question using the PICOT elements will provide a framework for the research you need to conduct an evidence-based study or to make an evidence-based decision.

    **PICOT Elements:**

    **(P)** –
    **Population, Patients or Problem**: The sample of subjects used in a study, or the problem being addressed.

    **(I)** –
    **Intervention**:  The treatment that will be provided to subjects enrolled in your study.

    **(C)** –
    **Comparison or Control**:  Identifies an alternative intervention or treatment to compare. Many study designs refer to this as the control group. If an existing treatment is considered the ‘gold standard’, then it should be the comparison group. A control group is not required for every type of study.

    **(O)** –
    **Outcome**: The clinical outcome that measures the effectiveness of the intervention.

    **(T)** –
    **Time**: Duration of the data collection.  Some versions don't include this element, and time may not be specified in cases where the question is focused on prediction or diagnoses.

    **PICOT Question Format Examples:**

    Please be sure to check your assignment, as it may direct you to use a different format.

    ·
    **Intervention:** In _______ (P), how does _______ (I) compared to  _______  (C) affect _______  (O) within _______ (T)?

    ·
    **Prognosis/Prediction**:  In _______ (P), how does _______ (I) compared to _______ (C) influence/predict _______ (O) over _______ (T)?

    ·
    **Diagnosis or Diagnostic test**:  In _______   (P) are/is _______   (I) compared to _______ (C) more accurate in diagnosing _______ (O)?

    ·
    **Etiology**:  Are _______ (P), who have _______ (I) compared to those without _______ (C) at _______ risk for/of _______ (O) over _______ (T)?

    ·
    **Meaning**:  How do_______ (P) with _______ (I) perceive _______ (O) during _______ (T)?

    **Example PICOT Questions:**

    · For residents of long-term care facilities (P), how does implementation of a hydration assessment tool (I) compared to current practice (C) affect the number of hospital admissions with the diagnosis of dehydration (O) during a three-month period (T)?

    · In acute care hospitals (P), how does having a rapid response team (I) compared with not having a response team (C) affect the number of cardiac arrests (O) during a three-month period (T)?

    · In women with gestational diabetes (P), how does a monitored diet and exercise program over the course of pregnancy (I &T), compare to the use of metformin only (C) reduce the incidence of high birth weight babies(O)?

    · In patients admitted for acute myocardial infarction (P), how well does the hospital's new data model created from EMR data (I) compared to current practices (C) predict readmission rates (O) within 30 days after initial discharge (T)?

    · For patients of a rural health clinic (P), does the use of text message reminders (I), compared with telephone calls (C) reduce the number of missed appointments (O) over a six month period (T)?

    **References:**

    ·
    [Melnyk, B.M., Fineout-Overholt, E., Stillwell, S. & Williamson, K. M. (2010). Evidence-Based Practice: Step by Step: The Seven Steps of Evidence-Based Practice. AJN, American Journal of Nursing, 110, 51-53.](http://library.capella.edu/login?url=http://ovidsp.ovid.com.library.capella.edu/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00000446-201001000-00030&LSLINK=80&D=ovft)

    · Melnyk, B. M., & Fineout-Overholt, E. (2015). Evidence-based practice in nursing & healthcare: A guide to best practice. (Not in library)

    **Additional Requirements:**

    Your assessment should meet the following requirements:

    ·
    **Length of submission**: Create a 3-5 page submission focused on defining a research question and interpreting evidence relevant to answering it.

    ·
    **Number of references**: Cite a minimum of four sources of scholarly or professional evidence that support your findings and considerations. Resources should be no more than 5 years old.

    ·
    **APA formatting:** Format references and citations according to the current APA style.

    **## C5A3Example.pdf**

    1

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    Learner’s Name

    Instructor Name

    August, 2020

    2

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    When developing care practices for patients, the PICO(T) research framework, which

    expands to Population/Patient, Intervention, Comparison, Outcome, and Time, can be used to

    create an effective care plan and ensure that patients’ needs are met. Relying on secondary

    research, the author of this paper will define a practice issue surrounding patients with dementia,

    apply the PICO(T) process, identify sources of evidence that may provide answers to the

    research question, explain key findings from articles, and explain the relevance of those key

    findings.

    Use of the PICO(T) Approach when Caring for Patients with Dementia

    The practice issue identified for resolution is the need to develop care practices that

    effectively manage agitation in patients with dementia in nursing homes that are outside of

    pharmacological approaches. The question being explored is: Is the non-pharmacological

    approach, specifically an intervention approach, more effective than the pharmacological

    approach in managing behavioral symptoms (such as agitation) in patients with dementia?

    The intervention approach identified is person-centered care or patient-centered care

    (PCC), an approach that emphasizes more on an individual’s experiences and the communication

    of his or her needs than on the pure implementation of a health care provider’s expertise (Desai,

    et al., 2017). The population being studied are patients with dementia with agitative behavioral

    symptoms in nursing homes. As the objective is to explore care practices that address this issue,

    only factors related to care in nursing homes are considered. The study does not take into

    consideration cultural, political, and social factors (Kim & Park, 2017).

    Identification of Sources of Evidence

    DICE Model

    3

    The DICE (Describe, Investigate, Create, and Evaluate) model is a notable PCC

    intervention model that identifies optimal treatment options for patients with dementia with

    neuropsychiatric symptoms. Developed by a panel of interdisciplinary experts at the University

    of Michigan Program for Positive Aging, the model is constitutive of a four-step approach. The

    first step of the approach is the accurate description of the patient’s behavior, the second is the

    identification of possible underlying causes, the third is the creation and implementation of

    treatment plans, and the fourth is the assessment of the strategies developed (Desai et al., 2017;

    Kales et al., 2014).

    The model’s essential recommendations for facilitating improvement in neuropsychiatric

    symptoms among patients with dementia are educating the caregiver; forging better

    communication between the patient and the caregiver; assisting the caregiver in organizing

    meaningful activities such as cooking, painting, or reading depending on the patient’s interests;

    and training the caregiver on simplifying his or her work routines (Desai et al., 2017; Kales et al.,

    2014).

    Individualized Intervention Model

    The individualized intervention model is a model in which intervention activities are carried

    out based on the history, needs, abilities, and preferences of patients with dementia. In this

    model, PCC-based activities are directly carried out by trained health care staff with expertise in

    social work, recreational therapy, geriatric psychiatry, and psychology (Kim & Park, 2017).

    Care Staff-Directed Model

    In the care staff–directed model, PCC activities are based on the staff’s education and

    training on empathy and person-centeredness. The model also makes a provision for offering

    4

    staff regular feedback for their work. The intervention period in such a model ranges from 3

    months to 2 years (Kim & Park, 2017).

    Findings from Articles

    As PCC is a major nonpharmacological approach to treating agitation in patients with

    dementia, its effectiveness is studied by making a comparative analysis to the pharmacological

    approach to manage behavioral symptoms in patients with dementia. Pharmacological treatment

    in general refers to the use of psychotropic medication to manage agitation or neuropsychotic

    symptoms (NPS) in patients with dementia (Madhusoodanan & Ting, 2014; Kales et al., 2014).

    Some of the common pharmacological interventions include the use of antipsychotropics,

    antidepressants such as sertraline and citalopram, and sedative-hypnotics through the use of

    benzodiazepines to control acute agitation (Madhusoodanan & Ting, 2014). The use of

    psychotropic medication poses high risks of mortality and harmful side effects (Kales et al.,

    2014). Psychotropic medication is also expensive and is restricted by regulatory bodies.

    However, the use of pharmacological intervention is justified when the benefits outweigh the

    risks or in situations wherein nonpharmacological interventions have proven unsuccessful

    (Madhusoodanan & Ting, 2014).

    The PCC approach has proven effective in addressing the etiology of aggressive

    outbursts. Unlike the pharmacological approach, which is based on treating symptoms, the PCC

    approach contributes to the resolution of underlying causes (Desai et al., 2017). The study by

    Kales et al. (2014) finds reasonable evidence of the DICE program’s contribution toward better

    clinical practices and improvement in aggressive behavior, and it observes that the approach

    results in fewer hospitalizations and readmissions. In their systematic review and meta-analysis

    of 19 primary studies, Kim and Park (2017) found 15 studies that measure the impact of PCC on

    5

    agitation using the Cohen-Mansfield Agitation Inventory (an agitation mapping instrument) and

    the Brief Agitation Rating Scale. They found that 8 of the 15 studies show positive effects on

    agitation with individualized interventions (with a significant mean difference of -0.513),

    showing better effects than with care staff–directed interventions (with a significant mean

    difference of -0.160).

    As this paper relies on secondary research on the PCC intervention to manage agitative

    behavior in patients with dementia in nursing homes, there are multiple time frames for the

    various intervention studies reviewed. While some studies had a long intervention period ranging

    from 9 months to 2 years, others had shorter intervention periods of just a few weeks. From the

    above exploration of the research problem based on the PICO(T) framework, it is clear that this

    framework has contributed to the delineation of precise intervention practices and has brought

    conceptual clarity on the issue of agitative behavior in patients with dementia.

    Relevance of Findings from Articles

    The study by Kales et al. (2014) was chosen as it provides a comprehensive explanation

    of the PCC-based DICE intervention program and its potential outcomes and draws an objective

    comparison of the program with pharmacological intervention. The study observed that the

    DICE model was developed by a panel of experts with years of clinical and research expertise in

    managing NPS in patients with dementia. The strategies formulated in the DICE approach were

    found to carry a strong evidence base. As it is evidence-informed, the DICE approach could be

    helpful for clinicians across diverse settings. Kales et al. (2014) conclude their study with a

    discussion on the potential of the DICE approach in enhancing clinical practices and ensuring the

    treatment of agitative behavior in patients with dementia.

    6

    The rationale for selecting the study by Kim and Park (2017) was that it presents a

    systematic review and meta-analysis of 19 primary intervention studies, of which 17 studies are

    from long-term care facilities. In their systematic review and meta-analysis of these studies, Kim

    and Park (2017) found that PCC has a significant impact on reducing NPS in patients with

    dementia. Kim and Park’s (2017) review found the increased engagement between care

    providers and patients and the magnitude of the program’s intensity to be the reasons for short-

    term PCC intervention having greater benefits in comparison to long-term intervention. The

    findings are relevant because they are based on 17 long-term, clinical PCC intervention studies

    comprising both controlled and non-controlled cluster-randomized trials conducted over the past

    10 years (Kim & Park, 2017).

    Kim & Park’s findings prove to be the most credible. In their systematic review and

    meta-analysis of primary studies, Kim and Park’s findings (2017) adhere to the guidelines of the

    Preferred Reporting Items for Systematic Reviews and Meta-Analyses. They also utilize analysis

    tools such as the Cochrane Collaboration’s risk of bias and the risk of bias assessment tool to

    ensure quality screening of the studies.

    Conclusion

    There is a need to develop care practices that are outside of pharmacological approaches

    for managing agitation in patients with dementia. The PICO(T) framework was applied to

    determine if the intervention approach of person-centered care or patient-centered care (PCC)

    was more effective than the pharmacological approach by identifying sources of evidence,

    explaining the findings and proving the relevance of those findings. The articles by Kales et al.

    (2014) and Kim and Park (2017), provide precise, reliable, and relevant information to

    adequately explore the effectiveness of the PCC approach.

    7

    References

    Desai, A., Wharton, T., Struble, L., & Blazek, M. (2017). Person-centered primary care

    strategies for assessment of and intervention for aggressive behaviors in dementia.

    Journal of Gerontological Nursing, 43(2), 9–17. https://search-proquest-

    com.library.capella.edu/docview/1862119355?pq-origsite=summon

    Kales, H. C., Gitlin, L. N., & Lyketsos, C. G. (2014). Management of neuropsychiatric

    symptoms of dementia in clinical settings: Recommendations from a multidisciplinary

    expert panel. Journal of the American Geriatrics Society, 62(4), 762–769.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/#

    Kim, S. K. & Park, M. (2017). Effectiveness of person-centered care on people with dementia: A

    systematic review and meta-analysis. Clinical Interventions in Aging, 12, 381–397.

    https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac

    Madhusoodanan, S., & Ting, M. B. (2014). Pharmacological management of behavioral

    symptoms associated with dementia. World Journal of Psychiatry, 4(4), 72–79.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/)

    [https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac](https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/)

    **## C5A3Example.pdf**

    1

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    Learner’s Name

    Instructor Name

    August, 2020

    2

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    When developing care practices for patients, the PICO(T) research framework, which

    expands to Population/Patient, Intervention, Comparison, Outcome, and Time, can be used to

    create an effective care plan and ensure that patients’ needs are met. Relying on secondary

    research, the author of this paper will define a practice issue surrounding patients with dementia,

    apply the PICO(T) process, identify sources of evidence that may provide answers to the

    research question, explain key findings from articles, and explain the relevance of those key

    findings.

    Use of the PICO(T) Approach when Caring for Patients with Dementia

    The practice issue identified for resolution is the need to develop care practices that

    effectively manage agitation in patients with dementia in nursing homes that are outside of

    pharmacological approaches. The question being explored is: Is the non-pharmacological

    approach, specifically an intervention approach, more effective than the pharmacological

    approach in managing behavioral symptoms (such as agitation) in patients with dementia?

    The intervention approach identified is person-centered care or patient-centered care

    (PCC), an approach that emphasizes more on an individual’s experiences and the communication

    of his or her needs than on the pure implementation of a health care provider’s expertise (Desai,

    et al., 2017). The population being studied are patients with dementia with agitative behavioral

    symptoms in nursing homes. As the objective is to explore care practices that address this issue,

    only factors related to care in nursing homes are considered. The study does not take into

    consideration cultural, political, and social factors (Kim & Park, 2017).

    Identification of Sources of Evidence

    DICE Model

    3

    The DICE (Describe, Investigate, Create, and Evaluate) model is a notable PCC

    intervention model that identifies optimal treatment options for patients with dementia with

    neuropsychiatric symptoms. Developed by a panel of interdisciplinary experts at the University

    of Michigan Program for Positive Aging, the model is constitutive of a four-step approach. The

    first step of the approach is the accurate description of the patient’s behavior, the second is the

    identification of possible underlying causes, the third is the creation and implementation of

    treatment plans, and the fourth is the assessment of the strategies developed (Desai et al., 2017;

    Kales et al., 2014).

    The model’s essential recommendations for facilitating improvement in neuropsychiatric

    symptoms among patients with dementia are educating the caregiver; forging better

    communication between the patient and the caregiver; assisting the caregiver in organizing

    meaningful activities such as cooking, painting, or reading depending on the patient’s interests;

    and training the caregiver on simplifying his or her work routines (Desai et al., 2017; Kales et al.,

    2014).

    Individualized Intervention Model

    The individualized intervention model is a model in which intervention activities are carried

    out based on the history, needs, abilities, and preferences of patients with dementia. In this

    model, PCC-based activities are directly carried out by trained health care staff with expertise in

    social work, recreational therapy, geriatric psychiatry, and psychology (Kim & Park, 2017).

    Care Staff-Directed Model

    In the care staff–directed model, PCC activities are based on the staff’s education and

    training on empathy and person-centeredness. The model also makes a provision for offering

    4

    staff regular feedback for their work. The intervention period in such a model ranges from 3

    months to 2 years (Kim & Park, 2017).

    Findings from Articles

    As PCC is a major nonpharmacological approach to treating agitation in patients with

    dementia, its effectiveness is studied by making a comparative analysis to the pharmacological

    approach to manage behavioral symptoms in patients with dementia. Pharmacological treatment

    in general refers to the use of psychotropic medication to manage agitation or neuropsychotic

    symptoms (NPS) in patients with dementia (Madhusoodanan & Ting, 2014; Kales et al., 2014).

    Some of the common pharmacological interventions include the use of antipsychotropics,

    antidepressants such as sertraline and citalopram, and sedative-hypnotics through the use of

    benzodiazepines to control acute agitation (Madhusoodanan & Ting, 2014). The use of

    psychotropic medication poses high risks of mortality and harmful side effects (Kales et al.,

    2014). Psychotropic medication is also expensive and is restricted by regulatory bodies.

    However, the use of pharmacological intervention is justified when the benefits outweigh the

    risks or in situations wherein nonpharmacological interventions have proven unsuccessful

    (Madhusoodanan & Ting, 2014).

    The PCC approach has proven effective in addressing the etiology of aggressive

    outbursts. Unlike the pharmacological approach, which is based on treating symptoms, the PCC

    approach contributes to the resolution of underlying causes (Desai et al., 2017). The study by

    Kales et al. (2014) finds reasonable evidence of the DICE program’s contribution toward better

    clinical practices and improvement in aggressive behavior, and it observes that the approach

    results in fewer hospitalizations and readmissions. In their systematic review and meta-analysis

    of 19 primary studies, Kim and Park (2017) found 15 studies that measure the impact of PCC on

    5

    agitation using the Cohen-Mansfield Agitation Inventory (an agitation mapping instrument) and

    the Brief Agitation Rating Scale. They found that 8 of the 15 studies show positive effects on

    agitation with individualized interventions (with a significant mean difference of -0.513),

    showing better effects than with care staff–directed interventions (with a significant mean

    difference of -0.160).

    As this paper relies on secondary research on the PCC intervention to manage agitative

    behavior in patients with dementia in nursing homes, there are multiple time frames for the

    various intervention studies reviewed. While some studies had a long intervention period ranging

    from 9 months to 2 years, others had shorter intervention periods of just a few weeks. From the

    above exploration of the research problem based on the PICO(T) framework, it is clear that this

    framework has contributed to the delineation of precise intervention practices and has brought

    conceptual clarity on the issue of agitative behavior in patients with dementia.

    Relevance of Findings from Articles

    The study by Kales et al. (2014) was chosen as it provides a comprehensive explanation

    of the PCC-based DICE intervention program and its potential outcomes and draws an objective

    comparison of the program with pharmacological intervention. The study observed that the

    DICE model was developed by a panel of experts with years of clinical and research expertise in

    managing NPS in patients with dementia. The strategies formulated in the DICE approach were

    found to carry a strong evidence base. As it is evidence-informed, the DICE approach could be

    helpful for clinicians across diverse settings. Kales et al. (2014) conclude their study with a

    discussion on the potential of the DICE approach in enhancing clinical practices and ensuring the

    treatment of agitative behavior in patients with dementia.

    6

    The rationale for selecting the study by Kim and Park (2017) was that it presents a

    systematic review and meta-analysis of 19 primary intervention studies, of which 17 studies are

    from long-term care facilities. In their systematic review and meta-analysis of these studies, Kim

    and Park (2017) found that PCC has a significant impact on reducing NPS in patients with

    dementia. Kim and Park’s (2017) review found the increased engagement between care

    providers and patients and the magnitude of the program’s intensity to be the reasons for short-

    term PCC intervention having greater benefits in comparison to long-term intervention. The

    findings are relevant because they are based on 17 long-term, clinical PCC intervention studies

    comprising both controlled and non-controlled cluster-randomized trials conducted over the past

    10 years (Kim & Park, 2017).

    Kim & Park’s findings prove to be the most credible. In their systematic review and

    meta-analysis of primary studies, Kim and Park’s findings (2017) adhere to the guidelines of the

    Preferred Reporting Items for Systematic Reviews and Meta-Analyses. They also utilize analysis

    tools such as the Cochrane Collaboration’s risk of bias and the risk of bias assessment tool to

    ensure quality screening of the studies.

    Conclusion

    There is a need to develop care practices that are outside of pharmacological approaches

    for managing agitation in patients with dementia. The PICO(T) framework was applied to

    determine if the intervention approach of person-centered care or patient-centered care (PCC)

    was more effective than the pharmacological approach by identifying sources of evidence,

    explaining the findings and proving the relevance of those findings. The articles by Kales et al.

    (2014) and Kim and Park (2017), provide precise, reliable, and relevant information to

    adequately explore the effectiveness of the PCC approach.

    7

    References

    Desai, A., Wharton, T., Struble, L., & Blazek, M. (2017). Person-centered primary care

    strategies for assessment of and intervention for aggressive behaviors in dementia.

    Journal of Gerontological Nursing, 43(2), 9–17. https://search-proquest-

    com.library.capella.edu/docview/1862119355?pq-origsite=summon

    Kales, H. C., Gitlin, L. N., & Lyketsos, C. G. (2014). Management of neuropsychiatric

    symptoms of dementia in clinical settings: Recommendations from a multidisciplinary

    expert panel. Journal of the American Geriatrics Society, 62(4), 762–769.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/#

    Kim, S. K. & Park, M. (2017). Effectiveness of person-centered care on people with dementia: A

    systematic review and meta-analysis. Clinical Interventions in Aging, 12, 381–397.

    https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac

    Madhusoodanan, S., & Ting, M. B. (2014). Pharmacological management of behavioral

    symptoms associated with dementia. World Journal of Psychiatry, 4(4), 72–79.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/)

    [https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac](https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/)

    **## C5A3Instructions.docx**

    **Instructions:**

    After reviewing the materials you created to research a specific diagnosis in the first two assessments, apply the PICO(T) process to develop a research question and research it.

    Your initial goal is to define the population, intervention, comparison, and outcome. In some cases, a time frame is relevant and you should include that as well, when writing a question you can research related to your issue of interest. After you define your question, research it, and organize your initial findings, select the two sources of evidence that seem the most relevant to your question and analyze them in more depth. Specifically, interpret each source's specific findings and best practices related to your chosen diagnosis, and explain how the evidence would help you plan and make decisions related to your question.

    If you need some structure to organize your initial thoughts and research, the PICOT Question and Research Template document (accessible from the "Create PICO(T) Questions" (BELOW) page in the Capella library's Evidence Based Practice guide) might be helpful.

    In your submission, make sure you address the following grading criteria:

    · Define a practice issue to be explored via a PICO(T) approach. Create a PICO(T)-formatted research question

    · Identify sources of evidence that could be potentially effective in answering a PICO(T) question (databases, journals, websites, etc.).

    · Explain the findings from articles or other sources of evidence as it relates to the identified health care issue.

    · Explain the relevance of the findings from chosen sources of evidence to making decision related to a PICO(T) question.

    · Communicate using writing that is clear, logical, and professional with correct grammar and spelling using the current APA style.

    **Create PICO(T) Questions:**

    **PICOT QUESTION PROCESS**

    Creating a question using the PICOT elements will provide a framework for the research you need to conduct an evidence-based study or to make an evidence-based decision.

    **PICOT Elements:**

    **(P)** –
    **Population, Patients or Problem**: The sample of subjects used in a study, or the problem being addressed.

    **(I)** –
    **Intervention**:  The treatment that will be provided to subjects enrolled in your study.

    **(C)** –
    **Comparison or Control**:  Identifies an alternative intervention or treatment to compare. Many study designs refer to this as the control group. If an existing treatment is considered the ‘gold standard’, then it should be the comparison group. A control group is not required for every type of study.

    **(O)** –
    **Outcome**: The clinical outcome that measures the effectiveness of the intervention.

    **(T)** –
    **Time**: Duration of the data collection.  Some versions don't include this element, and time may not be specified in cases where the question is focused on prediction or diagnoses.

    **PICOT Question Format Examples:**

    Please be sure to check your assignment, as it may direct you to use a different format.

    ·
    **Intervention:** In _______ (P), how does _______ (I) compared to  _______  (C) affect _______  (O) within _______ (T)?

    ·
    **Prognosis/Prediction**:  In _______ (P), how does _______ (I) compared to _______ (C) influence/predict _______ (O) over _______ (T)?

    ·
    **Diagnosis or Diagnostic test**:  In _______   (P) are/is _______   (I) compared to _______ (C) more accurate in diagnosing _______ (O)?

    ·
    **Etiology**:  Are _______ (P), who have _______ (I) compared to those without _______ (C) at _______ risk for/of _______ (O) over _______ (T)?

    ·
    **Meaning**:  How do_______ (P) with _______ (I) perceive _______ (O) during _______ (T)?

    **Example PICOT Questions:**

    · For residents of long-term care facilities (P), how does implementation of a hydration assessment tool (I) compared to current practice (C) affect the number of hospital admissions with the diagnosis of dehydration (O) during a three-month period (T)?

    · In acute care hospitals (P), how does having a rapid response team (I) compared with not having a response team (C) affect the number of cardiac arrests (O) during a three-month period (T)?

    · In women with gestational diabetes (P), how does a monitored diet and exercise program over the course of pregnancy (I &T), compare to the use of metformin only (C) reduce the incidence of high birth weight babies(O)?

    · In patients admitted for acute myocardial infarction (P), how well does the hospital's new data model created from EMR data (I) compared to current practices (C) predict readmission rates (O) within 30 days after initial discharge (T)?

    · For patients of a rural health clinic (P), does the use of text message reminders (I), compared with telephone calls (C) reduce the number of missed appointments (O) over a six month period (T)?

    **References:**

    ·
    [Melnyk, B.M., Fineout-Overholt, E., Stillwell, S. & Williamson, K. M. (2010). Evidence-Based Practice: Step by Step: The Seven Steps of Evidence-Based Practice. AJN, American Journal of Nursing, 110, 51-53.](http://library.capella.edu/login?url=http://ovidsp.ovid.com.library.capella.edu/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00000446-201001000-00030&LSLINK=80&D=ovft)

    · Melnyk, B. M., & Fineout-Overholt, E. (2015). Evidence-based practice in nursing & healthcare: A guide to best practice. (Not in library)

    **Additional Requirements:**

    Your assessment should meet the following requirements:

    ·
    **Length of submission**: Create a 3-5 page submission focused on defining a research question and interpreting evidence relevant to answering it.

    ·
    **Number of references**: Cite a minimum of four sources of scholarly or professional evidence that support your findings and considerations. Resources should be no more than 5 years old.

    ·
    **APA formatting:** Format references and citations according to the current APA style.

    **## C5A3Example.pdf**

    1

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    Learner’s Name

    Instructor Name

    August, 2020

    2

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    When developing care practices for patients, the PICO(T) research framework, which

    expands to Population/Patient, Intervention, Comparison, Outcome, and Time, can be used to

    create an effective care plan and ensure that patients’ needs are met. Relying on secondary

    research, the author of this paper will define a practice issue surrounding patients with dementia,

    apply the PICO(T) process, identify sources of evidence that may provide answers to the

    research question, explain key findings from articles, and explain the relevance of those key

    findings.

    Use of the PICO(T) Approach when Caring for Patients with Dementia

    The practice issue identified for resolution is the need to develop care practices that

    effectively manage agitation in patients with dementia in nursing homes that are outside of

    pharmacological approaches. The question being explored is: Is the non-pharmacological

    approach, specifically an intervention approach, more effective than the pharmacological

    approach in managing behavioral symptoms (such as agitation) in patients with dementia?

    The intervention approach identified is person-centered care or patient-centered care

    (PCC), an approach that emphasizes more on an individual’s experiences and the communication

    of his or her needs than on the pure implementation of a health care provider’s expertise (Desai,

    et al., 2017). The population being studied are patients with dementia with agitative behavioral

    symptoms in nursing homes. As the objective is to explore care practices that address this issue,

    only factors related to care in nursing homes are considered. The study does not take into

    consideration cultural, political, and social factors (Kim & Park, 2017).

    Identification of Sources of Evidence

    DICE Model

    3

    The DICE (Describe, Investigate, Create, and Evaluate) model is a notable PCC

    intervention model that identifies optimal treatment options for patients with dementia with

    neuropsychiatric symptoms. Developed by a panel of interdisciplinary experts at the University

    of Michigan Program for Positive Aging, the model is constitutive of a four-step approach. The

    first step of the approach is the accurate description of the patient’s behavior, the second is the

    identification of possible underlying causes, the third is the creation and implementation of

    treatment plans, and the fourth is the assessment of the strategies developed (Desai et al., 2017;

    Kales et al., 2014).

    The model’s essential recommendations for facilitating improvement in neuropsychiatric

    symptoms among patients with dementia are educating the caregiver; forging better

    communication between the patient and the caregiver; assisting the caregiver in organizing

    meaningful activities such as cooking, painting, or reading depending on the patient’s interests;

    and training the caregiver on simplifying his or her work routines (Desai et al., 2017; Kales et al.,

    2014).

    Individualized Intervention Model

    The individualized intervention model is a model in which intervention activities are carried

    out based on the history, needs, abilities, and preferences of patients with dementia. In this

    model, PCC-based activities are directly carried out by trained health care staff with expertise in

    social work, recreational therapy, geriatric psychiatry, and psychology (Kim & Park, 2017).

    Care Staff-Directed Model

    In the care staff–directed model, PCC activities are based on the staff’s education and

    training on empathy and person-centeredness. The model also makes a provision for offering

    4

    staff regular feedback for their work. The intervention period in such a model ranges from 3

    months to 2 years (Kim & Park, 2017).

    Findings from Articles

    As PCC is a major nonpharmacological approach to treating agitation in patients with

    dementia, its effectiveness is studied by making a comparative analysis to the pharmacological

    approach to manage behavioral symptoms in patients with dementia. Pharmacological treatment

    in general refers to the use of psychotropic medication to manage agitation or neuropsychotic

    symptoms (NPS) in patients with dementia (Madhusoodanan & Ting, 2014; Kales et al., 2014).

    Some of the common pharmacological interventions include the use of antipsychotropics,

    antidepressants such as sertraline and citalopram, and sedative-hypnotics through the use of

    benzodiazepines to control acute agitation (Madhusoodanan & Ting, 2014). The use of

    psychotropic medication poses high risks of mortality and harmful side effects (Kales et al.,

    2014). Psychotropic medication is also expensive and is restricted by regulatory bodies.

    However, the use of pharmacological intervention is justified when the benefits outweigh the

    risks or in situations wherein nonpharmacological interventions have proven unsuccessful

    (Madhusoodanan & Ting, 2014).

    The PCC approach has proven effective in addressing the etiology of aggressive

    outbursts. Unlike the pharmacological approach, which is based on treating symptoms, the PCC

    approach contributes to the resolution of underlying causes (Desai et al., 2017). The study by

    Kales et al. (2014) finds reasonable evidence of the DICE program’s contribution toward better

    clinical practices and improvement in aggressive behavior, and it observes that the approach

    results in fewer hospitalizations and readmissions. In their systematic review and meta-analysis

    of 19 primary studies, Kim and Park (2017) found 15 studies that measure the impact of PCC on

    5

    agitation using the Cohen-Mansfield Agitation Inventory (an agitation mapping instrument) and

    the Brief Agitation Rating Scale. They found that 8 of the 15 studies show positive effects on

    agitation with individualized interventions (with a significant mean difference of -0.513),

    showing better effects than with care staff–directed interventions (with a significant mean

    difference of -0.160).

    As this paper relies on secondary research on the PCC intervention to manage agitative

    behavior in patients with dementia in nursing homes, there are multiple time frames for the

    various intervention studies reviewed. While some studies had a long intervention period ranging

    from 9 months to 2 years, others had shorter intervention periods of just a few weeks. From the

    above exploration of the research problem based on the PICO(T) framework, it is clear that this

    framework has contributed to the delineation of precise intervention practices and has brought

    conceptual clarity on the issue of agitative behavior in patients with dementia.

    Relevance of Findings from Articles

    The study by Kales et al. (2014) was chosen as it provides a comprehensive explanation

    of the PCC-based DICE intervention program and its potential outcomes and draws an objective

    comparison of the program with pharmacological intervention. The study observed that the

    DICE model was developed by a panel of experts with years of clinical and research expertise in

    managing NPS in patients with dementia. The strategies formulated in the DICE approach were

    found to carry a strong evidence base. As it is evidence-informed, the DICE approach could be

    helpful for clinicians across diverse settings. Kales et al. (2014) conclude their study with a

    discussion on the potential of the DICE approach in enhancing clinical practices and ensuring the

    treatment of agitative behavior in patients with dementia.

    6

    The rationale for selecting the study by Kim and Park (2017) was that it presents a

    systematic review and meta-analysis of 19 primary intervention studies, of which 17 studies are

    from long-term care facilities. In their systematic review and meta-analysis of these studies, Kim

    and Park (2017) found that PCC has a significant impact on reducing NPS in patients with

    dementia. Kim and Park’s (2017) review found the increased engagement between care

    providers and patients and the magnitude of the program’s intensity to be the reasons for short-

    term PCC intervention having greater benefits in comparison to long-term intervention. The

    findings are relevant because they are based on 17 long-term, clinical PCC intervention studies

    comprising both controlled and non-controlled cluster-randomized trials conducted over the past

    10 years (Kim & Park, 2017).

    Kim & Park’s findings prove to be the most credible. In their systematic review and

    meta-analysis of primary studies, Kim and Park’s findings (2017) adhere to the guidelines of the

    Preferred Reporting Items for Systematic Reviews and Meta-Analyses. They also utilize analysis

    tools such as the Cochrane Collaboration’s risk of bias and the risk of bias assessment tool to

    ensure quality screening of the studies.

    Conclusion

    There is a need to develop care practices that are outside of pharmacological approaches

    for managing agitation in patients with dementia. The PICO(T) framework was applied to

    determine if the intervention approach of person-centered care or patient-centered care (PCC)

    was more effective than the pharmacological approach by identifying sources of evidence,

    explaining the findings and proving the relevance of those findings. The articles by Kales et al.

    (2014) and Kim and Park (2017), provide precise, reliable, and relevant information to

    adequately explore the effectiveness of the PCC approach.

    7

    References

    Desai, A., Wharton, T., Struble, L., & Blazek, M. (2017). Person-centered primary care

    strategies for assessment of and intervention for aggressive behaviors in dementia.

    Journal of Gerontological Nursing, 43(2), 9–17. https://search-proquest-

    com.library.capella.edu/docview/1862119355?pq-origsite=summon

    Kales, H. C., Gitlin, L. N., & Lyketsos, C. G. (2014). Management of neuropsychiatric

    symptoms of dementia in clinical settings: Recommendations from a multidisciplinary

    expert panel. Journal of the American Geriatrics Society, 62(4), 762–769.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/#

    Kim, S. K. & Park, M. (2017). Effectiveness of person-centered care on people with dementia: A

    systematic review and meta-analysis. Clinical Interventions in Aging, 12, 381–397.

    https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac

    Madhusoodanan, S., & Ting, M. B. (2014). Pharmacological management of behavioral

    symptoms associated with dementia. World Journal of Psychiatry, 4(4), 72–79.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/)

    [https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac](https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/)

    **## C5A3Instructions.docx**

    **Instructions:**

    After reviewing the materials you created to research a specific diagnosis in the first two assessments, apply the PICO(T) process to develop a research question and research it.

    Your initial goal is to define the population, intervention, comparison, and outcome. In some cases, a time frame is relevant and you should include that as well, when writing a question you can research related to your issue of interest. After you define your question, research it, and organize your initial findings, select the two sources of evidence that seem the most relevant to your question and analyze them in more depth. Specifically, interpret each source's specific findings and best practices related to your chosen diagnosis, and explain how the evidence would help you plan and make decisions related to your question.

    If you need some structure to organize your initial thoughts and research, the PICOT Question and Research Template document (accessible from the "Create PICO(T) Questions" (BELOW) page in the Capella library's Evidence Based Practice guide) might be helpful.

    In your submission, make sure you address the following grading criteria:

    · Define a practice issue to be explored via a PICO(T) approach. Create a PICO(T)-formatted research question

    · Identify sources of evidence that could be potentially effective in answering a PICO(T) question (databases, journals, websites, etc.).

    · Explain the findings from articles or other sources of evidence as it relates to the identified health care issue.

    · Explain the relevance of the findings from chosen sources of evidence to making decision related to a PICO(T) question.

    · Communicate using writing that is clear, logical, and professional with correct grammar and spelling using the current APA style.

    **Create PICO(T) Questions:**

    **PICOT QUESTION PROCESS**

    Creating a question using the PICOT elements will provide a framework for the research you need to conduct an evidence-based study or to make an evidence-based decision.

    **PICOT Elements:**

    **(P)** –
    **Population, Patients or Problem**: The sample of subjects used in a study, or the problem being addressed.

    **(I)** –
    **Intervention**:  The treatment that will be provided to subjects enrolled in your study.

    **(C)** –
    **Comparison or Control**:  Identifies an alternative intervention or treatment to compare. Many study designs refer to this as the control group. If an existing treatment is considered the ‘gold standard’, then it should be the comparison group. A control group is not required for every type of study.

    **(O)** –
    **Outcome**: The clinical outcome that measures the effectiveness of the intervention.

    **(T)** –
    **Time**: Duration of the data collection.  Some versions don't include this element, and time may not be specified in cases where the question is focused on prediction or diagnoses.

    **PICOT Question Format Examples:**

    Please be sure to check your assignment, as it may direct you to use a different format.

    ·
    **Intervention:** In _______ (P), how does _______ (I) compared to  _______  (C) affect _______  (O) within _______ (T)?

    ·
    **Prognosis/Prediction**:  In _______ (P), how does _______ (I) compared to _______ (C) influence/predict _______ (O) over _______ (T)?

    ·
    **Diagnosis or Diagnostic test**:  In _______   (P) are/is _______   (I) compared to _______ (C) more accurate in diagnosing _______ (O)?

    ·
    **Etiology**:  Are _______ (P), who have _______ (I) compared to those without _______ (C) at _______ risk for/of _______ (O) over _______ (T)?

    ·
    **Meaning**:  How do_______ (P) with _______ (I) perceive _______ (O) during _______ (T)?

    **Example PICOT Questions:**

    · For residents of long-term care facilities (P), how does implementation of a hydration assessment tool (I) compared to current practice (C) affect the number of hospital admissions with the diagnosis of dehydration (O) during a three-month period (T)?

    · In acute care hospitals (P), how does having a rapid response team (I) compared with not having a response team (C) affect the number of cardiac arrests (O) during a three-month period (T)?

    · In women with gestational diabetes (P), how does a monitored diet and exercise program over the course of pregnancy (I &T), compare to the use of metformin only (C) reduce the incidence of high birth weight babies(O)?

    · In patients admitted for acute myocardial infarction (P), how well does the hospital's new data model created from EMR data (I) compared to current practices (C) predict readmission rates (O) within 30 days after initial discharge (T)?

    · For patients of a rural health clinic (P), does the use of text message reminders (I), compared with telephone calls (C) reduce the number of missed appointments (O) over a six month period (T)?

    **References:**

    ·
    [Melnyk, B.M., Fineout-Overholt, E., Stillwell, S. & Williamson, K. M. (2010). Evidence-Based Practice: Step by Step: The Seven Steps of Evidence-Based Practice. AJN, American Journal of Nursing, 110, 51-53.](http://library.capella.edu/login?url=http://ovidsp.ovid.com.library.capella.edu/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00000446-201001000-00030&LSLINK=80&D=ovft)

    · Melnyk, B. M., & Fineout-Overholt, E. (2015). Evidence-based practice in nursing & healthcare: A guide to best practice. (Not in library)

    **Additional Requirements:**

    Your assessment should meet the following requirements:

    ·
    **Length of submission**: Create a 3-5 page submission focused on defining a research question and interpreting evidence relevant to answering it.

    ·
    **Number of references**: Cite a minimum of four sources of scholarly or professional evidence that support your findings and considerations. Resources should be no more than 5 years old.

    ·
    **APA formatting:** Format references and citations according to the current APA style.

    **## C5A3Example.pdf**

    1

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    Learner’s Name

    Instructor Name

    August, 2020

    2

    Using a PICO(T) Framework and Evidence to Develop Care Practices

    When developing care practices for patients, the PICO(T) research framework, which

    expands to Population/Patient, Intervention, Comparison, Outcome, and Time, can be used to

    create an effective care plan and ensure that patients’ needs are met. Relying on secondary

    research, the author of this paper will define a practice issue surrounding patients with dementia,

    apply the PICO(T) process, identify sources of evidence that may provide answers to the

    research question, explain key findings from articles, and explain the relevance of those key

    findings.

    Use of the PICO(T) Approach when Caring for Patients with Dementia

    The practice issue identified for resolution is the need to develop care practices that

    effectively manage agitation in patients with dementia in nursing homes that are outside of

    pharmacological approaches. The question being explored is: Is the non-pharmacological

    approach, specifically an intervention approach, more effective than the pharmacological

    approach in managing behavioral symptoms (such as agitation) in patients with dementia?

    The intervention approach identified is person-centered care or patient-centered care

    (PCC), an approach that emphasizes more on an individual’s experiences and the communication

    of his or her needs than on the pure implementation of a health care provider’s expertise (Desai,

    et al., 2017). The population being studied are patients with dementia with agitative behavioral

    symptoms in nursing homes. As the objective is to explore care practices that address this issue,

    only factors related to care in nursing homes are considered. The study does not take into

    consideration cultural, political, and social factors (Kim & Park, 2017).

    Identification of Sources of Evidence

    DICE Model

    3

    The DICE (Describe, Investigate, Create, and Evaluate) model is a notable PCC

    intervention model that identifies optimal treatment options for patients with dementia with

    neuropsychiatric symptoms. Developed by a panel of interdisciplinary experts at the University

    of Michigan Program for Positive Aging, the model is constitutive of a four-step approach. The

    first step of the approach is the accurate description of the patient’s behavior, the second is the

    identification of possible underlying causes, the third is the creation and implementation of

    treatment plans, and the fourth is the assessment of the strategies developed (Desai et al., 2017;

    Kales et al., 2014).

    The model’s essential recommendations for facilitating improvement in neuropsychiatric

    symptoms among patients with dementia are educating the caregiver; forging better

    communication between the patient and the caregiver; assisting the caregiver in organizing

    meaningful activities such as cooking, painting, or reading depending on the patient’s interests;

    and training the caregiver on simplifying his or her work routines (Desai et al., 2017; Kales et al.,

    2014).

    Individualized Intervention Model

    The individualized intervention model is a model in which intervention activities are carried

    out based on the history, needs, abilities, and preferences of patients with dementia. In this

    model, PCC-based activities are directly carried out by trained health care staff with expertise in

    social work, recreational therapy, geriatric psychiatry, and psychology (Kim & Park, 2017).

    Care Staff-Directed Model

    In the care staff–directed model, PCC activities are based on the staff’s education and

    training on empathy and person-centeredness. The model also makes a provision for offering

    4

    staff regular feedback for their work. The intervention period in such a model ranges from 3

    months to 2 years (Kim & Park, 2017).

    Findings from Articles

    As PCC is a major nonpharmacological approach to treating agitation in patients with

    dementia, its effectiveness is studied by making a comparative analysis to the pharmacological

    approach to manage behavioral symptoms in patients with dementia. Pharmacological treatment

    in general refers to the use of psychotropic medication to manage agitation or neuropsychotic

    symptoms (NPS) in patients with dementia (Madhusoodanan & Ting, 2014; Kales et al., 2014).

    Some of the common pharmacological interventions include the use of antipsychotropics,

    antidepressants such as sertraline and citalopram, and sedative-hypnotics through the use of

    benzodiazepines to control acute agitation (Madhusoodanan & Ting, 2014). The use of

    psychotropic medication poses high risks of mortality and harmful side effects (Kales et al.,

    2014). Psychotropic medication is also expensive and is restricted by regulatory bodies.

    However, the use of pharmacological intervention is justified when the benefits outweigh the

    risks or in situations wherein nonpharmacological interventions have proven unsuccessful

    (Madhusoodanan & Ting, 2014).

    The PCC approach has proven effective in addressing the etiology of aggressive

    outbursts. Unlike the pharmacological approach, which is based on treating symptoms, the PCC

    approach contributes to the resolution of underlying causes (Desai et al., 2017). The study by

    Kales et al. (2014) finds reasonable evidence of the DICE program’s contribution toward better

    clinical practices and improvement in aggressive behavior, and it observes that the approach

    results in fewer hospitalizations and readmissions. In their systematic review and meta-analysis

    of 19 primary studies, Kim and Park (2017) found 15 studies that measure the impact of PCC on

    5

    agitation using the Cohen-Mansfield Agitation Inventory (an agitation mapping instrument) and

    the Brief Agitation Rating Scale. They found that 8 of the 15 studies show positive effects on

    agitation with individualized interventions (with a significant mean difference of -0.513),

    showing better effects than with care staff–directed interventions (with a significant mean

    difference of -0.160).

    As this paper relies on secondary research on the PCC intervention to manage agitative

    behavior in patients with dementia in nursing homes, there are multiple time frames for the

    various intervention studies reviewed. While some studies had a long intervention period ranging

    from 9 months to 2 years, others had shorter intervention periods of just a few weeks. From the

    above exploration of the research problem based on the PICO(T) framework, it is clear that this

    framework has contributed to the delineation of precise intervention practices and has brought

    conceptual clarity on the issue of agitative behavior in patients with dementia.

    Relevance of Findings from Articles

    The study by Kales et al. (2014) was chosen as it provides a comprehensive explanation

    of the PCC-based DICE intervention program and its potential outcomes and draws an objective

    comparison of the program with pharmacological intervention. The study observed that the

    DICE model was developed by a panel of experts with years of clinical and research expertise in

    managing NPS in patients with dementia. The strategies formulated in the DICE approach were

    found to carry a strong evidence base. As it is evidence-informed, the DICE approach could be

    helpful for clinicians across diverse settings. Kales et al. (2014) conclude their study with a

    discussion on the potential of the DICE approach in enhancing clinical practices and ensuring the

    treatment of agitative behavior in patients with dementia.

    6

    The rationale for selecting the study by Kim and Park (2017) was that it presents a

    systematic review and meta-analysis of 19 primary intervention studies, of which 17 studies are

    from long-term care facilities. In their systematic review and meta-analysis of these studies, Kim

    and Park (2017) found that PCC has a significant impact on reducing NPS in patients with

    dementia. Kim and Park’s (2017) review found the increased engagement between care

    providers and patients and the magnitude of the program’s intensity to be the reasons for short-

    term PCC intervention having greater benefits in comparison to long-term intervention. The

    findings are relevant because they are based on 17 long-term, clinical PCC intervention studies

    comprising both controlled and non-controlled cluster-randomized trials conducted over the past

    10 years (Kim & Park, 2017).

    Kim & Park’s findings prove to be the most credible. In their systematic review and

    meta-analysis of primary studies, Kim and Park’s findings (2017) adhere to the guidelines of the

    Preferred Reporting Items for Systematic Reviews and Meta-Analyses. They also utilize analysis

    tools such as the Cochrane Collaboration’s risk of bias and the risk of bias assessment tool to

    ensure quality screening of the studies.

    Conclusion

    There is a need to develop care practices that are outside of pharmacological approaches

    for managing agitation in patients with dementia. The PICO(T) framework was applied to

    determine if the intervention approach of person-centered care or patient-centered care (PCC)

    was more effective than the pharmacological approach by identifying sources of evidence,

    explaining the findings and proving the relevance of those findings. The articles by Kales et al.

    (2014) and Kim and Park (2017), provide precise, reliable, and relevant information to

    adequately explore the effectiveness of the PCC approach.

    7

    References

    Desai, A., Wharton, T., Struble, L., & Blazek, M. (2017). Person-centered primary care

    strategies for assessment of and intervention for aggressive behaviors in dementia.

    Journal of Gerontological Nursing, 43(2), 9–17. https://search-proquest-

    com.library.capella.edu/docview/1862119355?pq-origsite=summon

    Kales, H. C., Gitlin, L. N., & Lyketsos, C. G. (2014). Management of neuropsychiatric

    symptoms of dementia in clinical settings: Recommendations from a multidisciplinary

    expert panel. Journal of the American Geriatrics Society, 62(4), 762–769.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/#

    Kim, S. K. & Park, M. (2017). Effectiveness of person-centered care on people with dementia: A

    systematic review and meta-analysis. Clinical Interventions in Aging, 12, 381–397.

    https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac

    Madhusoodanan, S., & Ting, M. B. (2014). Pharmacological management of behavioral

    symptoms associated with dementia. World Journal of Psychiatry, 4(4), 72–79.

    https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon](https://search-proquest-com.library.capella.edu/docview/1862119355?pq-origsite=summon)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4146407/)

    [https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac](https://doaj.org/article/400107a4cbaa44e6b7c0e3531bb4abac)

    [https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/](https://ncbi.nlm.nih.gov/pmc/articles/PMC4274589/)